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CHAPTER 14 - GASTROINTESTINAL TRACT
Histology Guide
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MICROSCOPE SLIDE

SLIDE NAME
MHS 273 Ileum
TISSUE
Ileum
(small intestine)
STAIN
Hematoxylin & Eosin
IMAGE SIZE
40,829 x 33,369 pixels
5.1 GB
FILE SIZE
222 MB
OBJECTIVE
40x
PIXEL SIZE
0.3171 µm
SOURCE
T. Clark Brelje and Robert L. Sorenson
Department of Genetics, Cell Biology, and Development
School of Medicine
University of Minnesota
Minneapolis, MN

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Robert L. Sorenson, Ph.D.

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University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455

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MHS 273 Ileum

Ileum

The ileum is the last location in which most nutrients are absorbed. It is composed of the four layers characteristic of the gastrointestinal tract.

  • (or mucous membrane)
    • - shorter, wide projections with blunt ends that extend into the lumen.
      • Absorptive Cells (or Enterocytes) - simple columnar cells with microvilli (or brush border) to expand the absorptive surface.
      • Goblet Cells - secrete mucus for lubrication.
    • - intestinal glands found at the base of villi.
    • Lamina Propria - loose connective tissue that supports the epithelium and forms the core of villi.
      • - lymphoid tissue found in the intestinal wall (GALT).
      • - prominent within the core of villi in the ileum.
    • - layer of smooth muscle.
  • - dense irregular connective tissue.
    • No submucosal glands (only in the duodenum).
  • - two orthogonal layers of smooth muscle (inner circular and outer longitudinal).
  • Adventitia - loose connective tissue (absent in this specimen).
© 2005-2026. T. Clark Brelje and Robert L. Sorenson