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CHAPTER 14 - GASTROINTESTINAL TRACT
Histology Guide
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MICROSCOPE SLIDE

SLIDE NAME
MH 119 Ileum
TISSUE
Ileum
(small intestine)
(human)
STAIN
Hematoxylin & Eosin
FIXATIVE
Zenker's Formaldehyde
IMAGE SIZE
59,228 x 34,921 pixels
7.7 GB
FILE SIZE
358 MB
OBJECTIVE
40x
PIXEL SIZE
0.3171 µm
SOURCE
Department of Genetics, Cell Biology, and Development
School of Medicine
University of Minnesota
Minneapolis, MN

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University of Minnesota
Department of Genetics, Cell Biology and Development
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321 Church St SE
Minneapolis, MN 55455

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MH 119 Ileum

Ileum

The absorptive surface of the small intestine is increased by microvilli, villi and plicae circularis.

  • (or mucous membrane)
    • - tall, slender finger-like projections.
      • (or Enterocytes) - simple columnar cells with microvilli (or brush border) and terminal web.
      • - secrete mucus for lubrication.
    • - intestinal glands at the base of villi.
      • - strongly eosinophilic cells in crypts.
      • Stem Cells - all of the intestinal epithelial cells arise from stem cells in crypts.
    • - loose connective tissue that supports the epithelium and forms the core of villi.
    • - supports the epithelium and villi.
  • - connective tissue with permanent folds that circle the inner surface of the intestinal lumen to form (circular folds, folds of Kerckring).
    • (or submucosal plexus) - provides secretory innervation of goblet cells and motor innervation of the muscularis mucosae. (Difficult to see in this specimen.)
    • No submucosal glands (only in the duodenum).
  • - two orthogonal layers of smooth muscle (inner circular and outer longitudinal).
    • (or myenteric plexus) - provides motor innervation of the muscularis externa.
  • - loose connective tissue.
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