Alan Peters and Claire Folger Sethares
The Fine Structure of the Aging Brain
(www.bu.edu/agingbrain)
Department of Anatomy & Cell Biology
Boston University School of Medicine
72 East Newton Street
Boston, Massachusetts
(Supported by the Institute on Aging of the National Institute of Health, Grant Number P 01-AG 000001)
Copying or redistribution in any manner for commercial use, including commercial publication, or for personal gain is strictly prohibited.
Faculty/Retired
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
Robert L. Sorenson, Ph.D.
Professor Emeritus
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
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EM 404 Node of Ranvier
Node of Ranver
Transmission electron microscopy (TEM) of a branching myelinated nerve fiber in the visual cortex.
Nodes of Ranvier are small gaps between segments of the myelin sheath that encircle the myelinated axons of neurons. A myelinated axon branches at a node of Ranvier.
Myelinated Nerve Fiber
Oligodendrocytes (brown)
Internodal Segments ( and ; dark brown) – covered by myelin sheaths
Paranodal Segments ( and ; light green) – lamellae terminate in sequential swellings on each side of the node
Axon (yellow) – branches at the node into two myelinated nerve fibers
Courtesy of Alan Peters and Claire Folger Sethares, The Fine Structure of the Aging Brain (www.bu.edu/agingbrain), Boston University School of Medicine, Boston, MA.
