Alan Peters and Claire Folger Sethares
The Fine Structure of the Aging Brain
(www.bu.edu/agingbrain)
Department of Anatomy & Cell Biology
Boston University School of Medicine
72 East Newton Street
Boston, Massachusetts
(Supported by the Institute on Aging of the National Institute of Health, Grant Number P 01-AG 000001)
Copying or redistribution in any manner for commercial use, including commercial publication, or for personal gain is strictly prohibited.
Faculty/Retired
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
Robert L. Sorenson, Ph.D.
Professor Emeritus
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
Each slide is shown with additional information to its right. The image can be changed using any combination of the following commands.
Sidebar
Click on links to move to a specific region.
Click on images to show that view.
Use the toolbar to change the magnification and pan the displayed image.
Mouse
Click to zoom-in
Double-click to zoom-out
Alt-click to zoom-out
Alt-double-click to zoom-out to the entire slide
Drag the image to pan
Keyboard
Shift or ‘A’ key to zoom-in
Ctrl or ‘Z’ Key to zoom-out
Arrow Keys to pan across the image
ESC key to zoom-out to the entire slide
Touch
Tap to zoom-in
Double-tap to zoom-out
Alt-tap to zoom-out to the entire slide
Drag the image to pan
SHARE
A link to a micrograph can be saved for later viewing in different ways.
Clipboard
The address of this view has been copied to your clipboard. This link can be pasted in any other program.
Bookmark
A bookmark link can be created using the bookmark function (Ctrl-D for Windows or Cmd-D for Mac) of your browser. Choose a name for the bookmark and select the folder in which you want it saved.
EM 403 Node of Ranvier
Node of Ranver
Transmission electron microscopy (TEM) of myelinated nerve fibers in the visual cortex.
Nodes of Ranvier are small gaps between segments of the myelin sheath that encircle the myelinated axons of neurons. A myelinated axon with a node of Ranvier runs diagonally across the image. The small, myelinated axon adjacent to the fiber is not part of the node.
Oligodendrocytes (green) – from up to 50 segments along multiple axons
Internodal Segments ( and ; dark green) – long regions covered by myelin sheath
Paranodal Segments ( and ; light green) – lamellae terminate in sequential swellings on each side of the node
Seal the myelin sheath with the axon
Isolates the space between the axon and the myelin sheath from the extracellular environment at the node
– cell membrane of the axon is only covered by processes
Courtesy of Alan Peters and Claire Folger Sethares, The Fine Structure of the Aging Brain (www.bu.edu/agingbrain), Boston University School of Medicine, Boston, MA.
