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CHAPTER 15 - LIVER AND GALLBLADDER
Histology Guide
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MICROGRAPH

NAME
EM 250 Kupffer Cell
(endothelium)
TISSUE
Liver
IMAGE SIZE
5,425 x 4,150 pixels
64 MB
FILE SIZES
21,281 (grayscale)
20,616 KB (color)
MAGNIFICATION
Unknown
PIXEL SIZE
6.175 nm
SOURCE
W. Deimann
H.D. Fahmi
Department of Anatomy
University of Heidelberg
Heidelberg, Germany

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EM 250 Kupffer Cell

Kupffer Cell

Scanning electron microscopy (SEM) of Kupffer cell in a liver sinusoid in the act of phagocytosis of a red blood cell.

Kupffer cells remove pathogens and pathogen-derived products (for example, lipopolysaccharides and foreign proteins). They also engulf and break down old red blood cells.

  • (orange)
  • (red)
  • (tan) - endothelial cells with fenestrations without diaphragms
  • (cyan) - cellular details cannot be discerned

The cell surface of macrophages is very dynamic during phagocytosis and movement. The thin undulating folds are called lamellipodia.

Courtesy of W. Deimann and H.D. Fahmi, Department of Anatomy, University of Heidelberg, Heidelberg, Germany.

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