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CHAPTER 2 - EPITHELIUM
Histology Guide
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MICROGRAPH

NAME
EM 034 Small Intestine
TISSUE
Rat Ileum
IMAGE SIZE
8,675 x 10,958 pixels
363 MB
FILE SIZES
70,930 KB (grayscale)
74,149 KB (color)
MAGNIFICATION
3,000x
PIXEL SIZE
3.825 nm
SOURCE
David G. Chase
Veteran's Administration Hospital
Sepulveda
CA

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University of Minnesota
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Robert L. Sorenson, Ph.D.

Professor Emeritus
University of Minnesota
Department of Genetics, Cell Biology and Development
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321 Church St SE
Minneapolis, MN 55455

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EM 034 Small Intestine

Simple Columnar Epithelium

A simple columnar epithelium with goblet cells lines the small intestine.

  • (dark green) - secrete mucins (the main component of mucus). Their goblet shape is due to secretion granules expanding the apical region of the cell.
    • (purple) - large, densely packed in the apical region of the cell.
    • (yellow) - well developed in this secretory cell.
    • (cyan) - abundant in the basal region of the cell
  • (enterocytes; light green) - most common type of cell in the small intestine. They are specialized for the absorption of nutrients.
    • (green) - thin extensions that increase the surface area of the apical membrane.
    • - complex of tight junctions (zonula occludens), zonula adherens and desmosomes (maculae adherens).
    • (red) - provide energy for the transport of molecules

The lateral of adjacent cells have extensive interdigitations.

The (dark purple) is the thin, fuzzy line that separates the epithelium from the underlying connective tissue. It has a network of reticular, collagen IV fibrils.

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