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CHAPTER 4 - MUSCLE TISSUE
Histology Guide
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MICROSCOPE SLIDE

SLIDE NAME
MHS 262 Skeletal Muscle
TISSUE
Skeletal Muscle
STAIN
Hematoxylin & Eosin
IMAGE SIZE
42,240 x 55,988 pixels
8.8 GB
FILE SIZE
37 MB
OBJECTIVE
40x
PIXEL SIZE
0.3171 µm
SOURCE
T. Clark Brelje and Robert L. Sorenson
Department of Genetics, Cell Biology, and Development
School of Medicine
University of Minnesota
Minneapolis, MN

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Robert L. Sorenson, Ph.D.

Professor Emeritus
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455

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MHS 262 Skeletal Muscle

Cross section of a skeletal muscle.

Connective tissue surrounds both individual and bundles of muscle fibers and is essential for force transduction.

Identify the three layers of connective tissue:

  • that surrounds each muscle fiber (arrows): [ + ]
    • Endomysium
  • that surrounds bundles of muscle fibers to form muscle fascicles: [ + ]
    • Perimysium
  • Sheath of that surrounds an entire muscle and is continuous with tendons: [ + ]
    • Epimysium

What structures are found in these layers of connective tissue? [ + ]

Blood vessels and nerves

What cell produces this connective tissue? [ + ]

Fibroblasts

(or fibers) are classified based on contractile speed and metabolic activity.

Describe Type I fibers (stain darker): [ + ]

Smaller muscle cells that specialize in long slow contractions

Describe Type II fibers (stain lighter): [ + ]

Larger muscle cells that specialize in fast contractions

What is the name of this ? [ + ]

Muscle spindle

Describe these ? [ + ]

Fluid filled capsules enclosing a few small muscle cells and nerve fibers

What is the function of these special sensory organs? [ + ]

Specialized stretch receptors that transmit information to motor neurons in the spinal cord innervating this muscle
© 2005-2026. T. Clark Brelje and Robert L. Sorenson