Histology Guide

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MICROSCOPE SLIDE

SLIDE NAMES

MHS 210 Thymus

TISSUE

Thymus

STAIN

Hematoxylin & Eosin

IMAGE SIZE

31,262 x 49,213 pixels
5.7 GB

FILE SIZE

333 MB

MAGNIFICATION

40x

PIXEL SIZE

0.3171 µm

SOURCE

Robert L. Sorenson
University of Minnesota
Minneapolis, MN

CONTACT

Questions or comments should be sent to
tcbrelje@gmail.com

This web site is owned and operated by:

T. Clark Brelje, Ph.D.

Faculty/Retired
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455

Robert L. Sorenson, Ph.D.

Professor Emeritus
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455

Version 5.0

Copyright © 2005-2021
T. Clark Brelje and Robert L. Sorenson
All rights reserved.

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MHS 210 Thymus

Thymus

Thymus is an encapsulated organ where T-cells proliferate and mature behind the blood-thymus barrier.

This slide has good examples of macrophages.

- thin connective tissue surrounding the thymus that extends trabeculae inward forming incomplete lobules.
- outer darker, region of small lymphocytes.
- - tightly packed, small nuclei of condensed chromatin
- - large cells with oval nuclei and lightly stained cytoplasm with processes. Their nuclei have euchromatin and a prominent nucleolus.
- Macrophages (, and ) - large cells that phagocytize T cells marked for removal. Many of the macrophages contain phagocytized lymphocytes with pyknotic nuclei.
- - round cells with oval nuclei and granules stained a bright red.
- Cortical Capillaries ( and ) - the site of the blood-thymus barrier.
- inner, lighter region of larger lymphocytes.
- - large cells with oval nuclei and lightly stained cytoplasm.
- Hassall's Corpuscle (, and ) - closely packed, concentrically arranged epithelial reticular cells.
- Post Capillary Venules ( and ) - have a wide lumen and the endothelial nuclei bulge into the lumen. This is the site where lymphocytes exit the thymus.