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CHAPTER 13 - ENDOCRINE GLANDS
Histology Guide
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MICROSCOPE SLIDE

SLIDE NAME
MH 154 Parathyroid
TISSUE
Parathyroid
(human)
STAIN
Hematoxylin & Eosin
IMAGE SIZE
23,745 x 17,034 pixels
1.5 GB
FILE SIZE
74 MB
OBJECTIVE
40x
PIXEL SIZE
0.3171 µm
SOURCE
Department of Genetics, Cell Biology, and Development
School of Medicine
University of Minnesota
Minneapolis, MN

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Department of Genetics, Cell Biology and Development
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MH 154 Parathyroid

Parathyroid

The parathyroid glands are located on the four poles of the thyroid. Parathyroid hormone (PTH) stimulates the release of calcium by bones, absorption of calcium from food and retention of calcium by the kidneys.

  • Stroma
    • - enclosed by a thin layer of connective tissue.
    • - connective tissue extends inwards from the capsule to partially outline irregular lobes and lobules.
  • Parenchyma
    • Chief Cells (,) - the majority of cells in the parathyroid.
      • Small cells (5 to 8 µm diameter) with dark nuclei and thin rim of lightly stained cytoplasm.
      • They secrete parathyroid hormone (PTH).
    • Oxyphil Cells (,) - larger cells (8 to 12 µm diameter) with dark nuclei and strongly eosinophilic cytoplasm because of numerous mitochondria. They appear after the first decade of life and are thought to be non-secretory cells.
    • Clear Cells (,)- larger cells (8 to 12 µm diameter) with dark nuclei and a watery, clear cytoplasm.
    • Adipose Cells (,) - increase with age.
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