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The parotid is the largest of the salivary glands. It is almost entirely serous with only a few scattered mucous cells.
Stroma - the connective tissue component of the gland.
Capsule - connective tissue that encapsulates the gland.
Lobes - connective tissue divides the gland into lobes.
Lobules - connective tissue further divides lobes into lobules - the smallest functional unit.
Parenchyma - the functional component of the gland that consists of secretory cells and ducts
Serous Cells - arranged in acini of pyramidal serous cells. These polarized cells have rough endoplasmic reticulum (RER) at their base (basophilic) and secretion granules (eosinophilic)
at their apex
Mucous Cells - polarized cells with flattened nuclei at the bottom of the cells. They are very lightly stained with a "foamy" appearance (mucous has been extracted).
Parotid
Intralobular Ducts - two types are found within lobules:
Intercalated Ducts (#1, #2 and #3)
- the smallest ducts that insert into and drain individual acini. They are more lightly stained than acini cells and are low cuboidal.
Striate Ducts - arise from intercalated ducts. They are columnar with basal striations and are surrounded by capillaries.
Interlobular (or Extralobular) Ducts (#1 and #2) - found outside of lobules.
Simple columnar, stratified columnar or stratified cuboidal epithelium.
Supported by a thick layer of connective tissue.
Note the abundance of adipose cells which increases with age.
