MH 051 Dorsal Root Ganglion

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Dorsal Root Ganglion
(Azan)

A cross-section of a dorsal root ganglion stained with azan to make it easier to see nerve fibers and connective tissue.

Compare this slide with MH 050 Dorsal Root Ganglion (H&E).

- large, nerve with large nuclei and prominent, red nucleoli. Their cytoplasm contains abundant Nissl substance.
- glial cells at the periphery of nerve cell bodies.
- non-myelinated and myelinated axons of different diameters seen in cross-section.
- Axon - light blue material at the center of each nerve fiber.
- Schwann Cells - glial cells that wrap axons in the peripheral nervous system. Their large, round nuclei are adjacent to some axons.
  - Myelin Sheath - pink/red material surrounding myelinated axons. Often has a fluted appearance.
- Endoneurium - connective tissue (dark blue) surrounding each nerve fiber.
- - a rare view of a myelinated axon
- their small nuclei are seen in the endoneurium. (Most frequent nuclei in cross-sections of nerve fibers.)
- dense irregular connective tissue (dark blue) that is continuous with the epineurium of the nerve.