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CHAPTER 13 - ENDOCRINE GLANDS
Histology Guide
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MICROGRAPH

NAME
RD 213 Pituitary
TISSUE
Anterior Pituitary
(pars distalis)
IMAGE SIZE
12,863 x 9,602 pixels
353 MB
FILE SIZES
88,591 KB (grayscale)
93,930 (color)
MAGNIFICATION
Unknown
PIXEL SIZE
1.591 nm
SOURCE
Ronald W. Dudek
Brody School of Medicine
East Carolina University
Greenville, North Carolina

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RD 213 Pituitary

Anterior Pituitary

Transmission electron micrograph (TEM) of the pars distalis of the anterior pituitary. Different types of cells can be identified by the morphology of their secretion granules.

  • (yellow) - secrete growth hormonr (GH)
    • Large, round granules (300 to 350 um in diameter) fill the cytoplasm
    • Most frequent cell found in the anterior pituitary
  • (green) - secrete prolactin (PRL)
    • Large, round to oval granules (500 to 800 um in diameter)
  • (red) - secrete thyroid stimulating hormone (TSH)
    • Smaller, round granules (120 to 150 um in diameter)
  • (blue) - secrete gonadotrophs which include follicle-stimulating hormone (FSH) and luteinizing hormone (LH)
    • Smaller, round secretion granules (200 to 250 um in diameter)
    • Often distended rough endoplasmic reticulum (RER)

The only other major cell type not visible is corticotrophs which secrete ACTH.

Subcellular Structures

  • Nucleus (blue) / Nuclear Envelope (purple)
  • Golgi Apparatus (yellow)
  • Mitochondria (red)
  • Endoplasmic Reticulum (cyan)
  • Secretion Granules(purple)

Courtesy of Ronald W. Dudek, Brody School of Medicine, East Carolina University, Greenville, North Carolina.

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