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CHAPTER 10 - LYMPHOID SYSTEM
Histology Guide
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MICROGRAPH

NAME
RD 114 spleen
TISSUE
Spleen
Red Pulp
IMAGE SIZE
10.478 x 9,324 pixels
277 MB
FILE SIZES
121,081 KB (grayscale)
145,411 KB (color)
MAGNIFICATION
Unknown
PIXEL SIZE
2.525 nm
SOURCE
Ronald W. Dudek
Brody School of Medicine
East Carolina University
Greenville, North Carolina

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RD 114 Spleen

Spleen

Transmission electron micrograph (TEM) of a splenic cord (cords of Billroth) from red pulp of the spleen. Most of the cells within splenic cords are macrophages, neutrophils, and lymphocytes.

A lymphocyte is crossing through a small opening in the sinusoid wall into a splenic cord.

  • (tan) - unusual structure compared to other capillaries
    • Endothelium - spindle-like cells with small gaps that allow easy passage of cells into and out of the capillary
  • (yellow) - wrap around reticular fibers composed of type III collagen
    • Framework for splenic cords and sinusoids
  • (green) - leaving the sinusoid and entering the splenic cord
  • (dark green)
  • (red)
  • (light blue)

Subcellular Structures

  • Nucleus (blue) / Nuclear Envelope (purple)
  • Golgi Apparatus (yellow)
  • Mitochondria (red)
  • Endoplasmic Reticulum (cyan)

Courtesy of Ronald W. Dudek, Brody School of Medicine, East Carolina University, Greenville, North Carolina.

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