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CHAPTER 9 - CARDIOVASCULAR SYSTEM
Histology Guide
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MICROGRAPH

NAME
EM 389 Vein
TISSUE
Unknown
IMAGE SIZE
8,264 x 11,732 pixels
291 MB
FILE SIZES
20,671 KB (grayscale)
26,391 KB (color)
MAGNIFICATION
Unknown
PIXEL SIZE
3.415 nm
SOURCE
Tatsuo Ebe
Shigeru Kobayashi
Niigata University of Medicine
Anatomy Department
Niigata, Japan

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EM 389 Vein

Vein

Transmission electron microscopy (TEM) of the wall of a vein.

Veins are blood vessels that carry deoxygenated blood from various parts of the body back to the heart. They have thinner walls compared to arteries and often contain valves to prevent backflow of blood.

Like other blood vessels, veins are composed of three layers (or tunics):

  • (red)) - inner layer of endothelial cells (endothelium
    • Attached to each other by tight junctions
    • Separated by the basal lamina (purple) from the other layers
  • (orange) - middle layer composed of smooth muscle
    • Thinner in veins compared to arteries
    • Many aggregates of glycogen granules (black)
    • Separated by the basal lamina (purple) from the outer layers
  • (green) - outer layer of irregular connective tissue
    • Thickest layer
    • Multiple layers of fibrocytes (green) are surrounded by collagen fibers (tan)
    • Provides structural support to the vein

A (red) is seen in the tunica adventitia in the lower left. These small blood vessels (vasa vasorum) supply the walls of larger blood vessels with oxygen and nutrients.

Subcellular Structures

  • Nuclei (blue) / Nuclear Envelope (purple)
  • Mitochondria (red)
  • Endoplasmic Reticulum (cyan)
  • Cytoplasm (red/tan/green)

Courtesy of Tatsuo Ebe and Shigeru Kobayashi, Niigata University of Medicine, Anatomy Department, Niigata, Japan.

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