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CHAPTER 12 - EXOCRINE GLANDS
Histology Guide
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MICROGRAPH

NAME
EM 373 Sebaceous Gland
TISSUE
Thin Skin
IMAGE SIZE
8,668 x 11,041 pixels
287 MB
FILE SIZES
39,809 KB (grayscale)
48,917 KB (color)
MAGNIFICATION
Unknown
PIXEL SIZE
2.689 nm
SOURCE
Karen Hollbrook
Department of Biological Structure
University of Washington
School of Medicine
Seattle, WA

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EM 373 Sebaceous Gland

Sebaceous Gland

Transmission electron microscopy (TEM) of the edge of a sebaceous gland in skin.

Sebaceous glands are exocrine glands in the skin that open into a hair follicle to secrete sebum, an oily or greasy substance that lubricates the hair and skin.

The gland is composed of acini which branch off a central duct.

  • (green) - large cells filled with the fatty secretory product (orange)
    • Holocrine Secretion - cells undergo programmed cell death (apoptosis), simultaneously releasing the secretory product and cell debris
  • (cyan) - undifferentiated cells at the periphery that replenish the lipogenic cells by mitosis

Many desmosomes (,; yellow) connect the cells of the gland.

A (purple) separates the gland from the surrounding connective tissue (tan). Hemidesmosomes (,; yellow) attach the cells to the basal lamina.

Subcellular Structures

  • Nuclei (blue) / Nuclear Envelope (purple)
  • Mitochondria (red)
  • Endoplasmic Reticulum (cyan)
  • Cytoplasm (green/cyan/tan)

Courtesy of Karen Hollbrook, Department of Biological Structure, University of Washington, School of Medicine, Seattle, WA.

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