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CHAPTER 16 - URINARY SYSTEM
Histology Guide
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MICROGRAPH

NAME
EM 193 Kidney
TISSUE
Rhesus Kidney
IMAGE SIZE
9,732 x 8,687 pixels
242 MB
FILE SIZES
40,186 KB (grayscale)
41,189 KB (color)
MAGNIFICATION
Unknown
PIXEL SIZE
57.25 nm
SOURCE
Stanley L. Erlandsen
Department of Genetics, Cell Biology and Development
School of Medicine
University of Minnesota
Minneapolis, MN

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EM 193 Kidney

Filtration Barrier

Transmission electron micrograph (TEM) of a fenestrated capillary within a glomerulus of a renal corpuscle.

The filtration barrier is composed of the fenestrated capillaries, a thick basement membrane, and the filtration slits of the podocytes.

  • (green) - endothelial cells have many (or fenestrations) lacking diaphragms
    • No cell bodies or nuclei are visible
  • (purple) - between the endothelium and podocytes
    • Much thicker (~300 to 340 nm) than in other tissues
  • (tan) - highly specialized epithelial cells that cover the outer surface of the basement membrane
    • (or pedicels) are spanned by thin slit diaphragms

The filtrate is collected in the urinary space of Bowman's capsule.

(cyan) and matrix (yellow) between capillary loops help keep the structure of the glomerulus and have a phagocytic role in maintaining the basement membrane.

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