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CHAPTER 3 - CONNECTIVE TISSUE
Histology Guide
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MICROGRAPH

NAME
EM 108 Mast Cell
TISSUE
Ileum
IMAGE SIZE
5,735 x 4,534 pixels
99 MB
FILE SIZES
24,060 KB (grayscale)
20,603 KB (color)
MAGNIFICATION
10,000x
PIXEL SIZE
3.204 nm
SOURCE
Stanley L. Erlandsen
Department of Genetics, Cell Biology and Development
School of Medicine
University of Minnesota
Minneapolis, MN

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EM 108 Mast Cell

Mast Cells

Mast cells are immune cells that migrate from blood into connective tissue. They engage in inflammatory responses by releasing molecules that dilate blood vessels and recruit other cells. They play a key role in allergic reactions.

A mast cell contains abundant, large granules that contain inflammatory substances (histamine and heparin). Stimulation by an antigen results in degranulation.

These are immature mast cells because of their small size.

  • (dark green) - short filopodia.
  • (blue) / (purple) - rounded to elongated.
  • (yellow) - not visible in the left cell, but well-developed in the right cell.
  • (red) - relatively few in number.
  • (cyan) - few scattered fragments.
  • (purple) - heterogeneous in size and contents.
  • Cytoplasm (green) - full of granules.
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