T. Clark Brelje, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
Robert L. Sorenson, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
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MHS 222 Trachea
Pseudostratified Columnar Epithelium
The luminal surface of the trachea is lined with a pseudostratified columnar epithelium. In some areas, individual epithelial cells can be identified in this semi-thin section.
Cilia - extend 5 to 7 µm from the surface of the epithelial cells. The dark line at their base is from their basal bodies.
Goblet Cells - scattered cells that secrete mucus. They are difficult to identify in this specimen.
Basement Membrane - the epithelium is separated from the underlying connective tissue by a thick basement membrane. It is seen as an eosinophilic band beneath the epithelium.
This pseudostratified ciliated, columnar epithelium with goblet cells is known as respiratory epithelium.
